カタログ製品コード : C-EK11012
Human sCD14 ELISA kit
| 24T | ¥128,200 | (¥5,342/T) (税別) |
| 48T | ¥142,200 | (¥2,963/T) (税別) |
| 96T | ¥151,000 | (¥1,573/T) (税別) |
標準納期 : 1週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | sCD14 | Human | 125 - 8000 pg/ml | 100 μl (prediluted) | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against CD14 |
| Human CD14 Standard, lyophilized |
| CD14 Detect Antibody |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Monocyte differentiation antigen CD14,Myeloid cell-specific leucine-rich glycoprotein,CD14,CD14
■ターゲット情報 :
"This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CD14. The Human sCD14 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
CD14 is expressed mainly by macrophages and (at 10-times lesser extent) by neutrophils. It is also expressed by dendritic cells. It is a component of the innate immune system. CD14 acts as a co-receptor for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). sCD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted
from intracellular vesicles (56 kDa). sCD14 is secreted by the liver and monocytes and is sufficient in low concentrations to confer LPS-responsiveness to cells not expressing CD14. mCD14 and sCD14 are also present on enterocytes. sCD14 is also present in human milk, where it is believed to regulate microbial growth in the infant gut."
