96-well polystyrene microplate coated with a monoclonal antibody against IL-1β
Human IL-1β Standard, lyophilized
IL-1β Detect Antibody
Amplification Reagent Concentrate
Assay Buffer (10×)
Washing Buffer (20×)
Homo sapiens,Human,Interleukin-1 beta,IL-1 beta,Catabolin,IL1B,IL1F2
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-1β. The Human IL-1β ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin-1 (IL-1) is an extracellular peptide of 17 kDa that designates two proteins, IL-1α and IL-1β. IL-1β is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.The interleukin-1 (IL-1) species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses. Increased production of IL-1β causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as CAPS, due to mutations in the inflammasome receptor NLRP3 which triggers processing of IL-1β.